4-Methyl-3-(trifluoromethyl)aniline

Names

[ Name ]:
4-Methyl-3-(trifluoromethyl)aniline

[Synonym ]:
4-Methyl-3-(trifluoromethyl)aniline
4-Methyl-3-(trifluormethyl)anilin
MFCD01631582
ZR D1 CXFFF
5-Amino-2-methylbenzotrifluoride
Benzenamine, 4-methyl-3-(trifluoromethyl)-
4-Methyl-3-(trifluoromethyl)benzenamine
3-(Trifluoromethyl)-p-toluidine

Chemical & Physical Properties

[ Density]:
1.220

[ Boiling Point ]:
204 ºC

[ Molecular Formula ]:
C₈H₈F₃N

[ Molecular Weight ]:
175.151

[ Flash Point ]:
102 ºC

[ Exact Mass ]:
175.060883

[ PSA ]:
26.02000

[ LogP ]:
2.85

[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.490

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
2810

[ WGK Germany ]:
3

[ HS Code ]:
2921430090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921430090

[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Design, synthesis, and biological evaluation of 3-(1 H-1, 2, 3-triazol-1-yl) benzamide derivatives as potent pan Bcr-Abl inhibitors including the threonine315? isoleucine315 mutant. Li Y, et al.

J. Med. Chem. 55(22) , 10033-10046, (2012)