DL-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL

Names

[ Name ]:
DL-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL

[Synonym ]:
Benzenemethanol, α-[(methylamino)methyl]-
win5529-2
1-Hydroxy-1-phenyl-2-methylaminoethane
Benzyl alcohol, α-((methylamino)methyl)-
N-Methylphenylethanolamine
MFCD00004506
HALOSTACHINE
UNII:U7B63FX8CH
2-(Methylamino)-1-phenylethanol
2-Methylamino-1-phenylethanol
2-(methylamino)-1-phenyl-ethano
EINECS 229-525-5
dl-α-(Methylaminomethyl)benzyl alcohol

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
244.1±7.0 °C at 760 mmHg

[ Melting Point ]:
74-76ºC

[ Molecular Formula ]:
C₉H₁₃NO

[ Molecular Weight ]:
151.206

[ Flash Point ]:
96.3±8.7 °C

[ Exact Mass ]:
151.099716

[ PSA ]:
32.26000

[ LogP ]:
0.71

[ Appearance of Characters ]:
Fine Crystalline Needles | White

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.537

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DO9625000

CHEMICAL NAME :: Benzyl alcohol, alpha-((methylamino)methyl)-

CAS REGISTRY NUMBER :: 6589-55-5

LAST UPDATED :: 199009

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H13-N-O

MOLECULAR WEIGHT :: 151.23

WISWESSER LINE NOTATION :: QYR&1M1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 106,341,1952

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 85 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 106,341,1952

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H332

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DO9625000

Articles

MMA/MPEOMA/VSA copolymer as a novel blood-compatible material: ex vivo platelet adhesion study.

J. Mater. Sci. Mater. Med. 15(2) , 155-9, (2004)

MMA/MPEOMA/VSA copolymers with both pendant polyethylene oxide (PEO) side chains and negatively chargeable side groups were synthesized by random copolymerization of methyl methacrylate (MMA), methoxy...

Phe310 in transmembrane VI of the alpha1B-adrenergic receptor is a key switch residue involved in activation and catecholamine ring aromatic bonding.

J. Biol. Chem. 274(23) , 16320-30, (1999)

Pharmacophore mapping of adrenergic receptors indicates that the phenyl ring of catecholamine agonists is involved in receptor binding and activation. Here we evaluated Phe310, Phe311, and Phe303 in t...

Characterization of N-methylphenylethylamine and N-methylphenylethanolamine as substrates for type A and type B monoamine oxidase.

Biochem. Pharmacol. 29(19) , 2663-7, (1980)