Distamycin A hydrochloride
Names
[ CAS No. ]:
6576-51-8
[ Name ]:
Distamycin A hydrochloride
[Synonym ]:
herperal
EINECS 229-505-6
estalimicinaclorhidrato
STALLIMYCIN HCL
fi6426
N''-(2-Amidinoethyl)-4-formamido-1,1',1''-trimethyl-N,4':N',4''-ter(pyrrole-2-carboxamide) monohydrochloride
distamycin A monohydrochloride
N-[5-({5-[(3-Amino-3-iminopropyl)carbamoyl]-1-methyl-1H-pyrrol-3-yl}carbamoyl)-1-methyl-1H-pyrrol-3-yl]-4-formamido-1-methyl-1H-pyrrole-2-carboxamide hydrochloride (1:1)
DISTAMYCIN A HCL
1H-Pyrrole-2-carboxamide, N-[5-[[(3-amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-4-[[[4-(formylamino)-1-methyl-1H-pyrrol-2-yl]carbonyl]amino]-1-methyl-, hydrochloride (1:1)
Distamycin A hydrochloride from Streptomyces distallicus
stallimycinhydrochloride
1H-Pyrrole-2-carboxamide, N-(5-(((3-amino-3-iminopropyl)amino)carbonyl)-1-methyl-1H-pyrrol-3-yl)-4-(((4-(formylamino)-1-methyl-1H-pyrrol-2-yl)carbonyl)amino)-1-methyl-, monohydrochloride
stallimycin monohydrochloride
N-(5-(((3-Amino-3-iminopropyl)amino)carbonyl)-1-methyl-1H-pyrrol-3-yl)-4-(((4-(formylamino)-1-methyl-1H-pyrrol-2-yl)carbonyl)amino)-1-methyl-1H-pyrrole-2-carboxamide monohydrochloride
distamycin A hydrochloride from*streptomyces dist
STALLIMYCIN HYDROCHLORIDE
Chemical & Physical Properties
[ Boiling Point ]:
715.4ºC at 760 mmHg
[ Molecular Formula ]:
C22H28ClN9O4
[ Molecular Weight ]:
517.969
[ Flash Point ]:
386.4ºC
[ Exact Mass ]:
517.195251
[ PSA ]:
181.06000
[ LogP ]:
3.67870
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WZ7110000
- CAS REGISTRY NUMBER :
- 6576-51-8
- LAST UPDATED :
- 199409
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C22-H27-N9-O4.Cl-H
- MOLECULAR WEIGHT :
- 518.04
- WISWESSER LINE NOTATION :
- T5NJ A1 BVM2YZUM DMV- BT5NJ A1 EMV- BT5NJ A1 DMVH &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 169 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 160 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 200 umol
- REFERENCE :
- EJBCAI European Journal of Biochemistry. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1967- Volume(issue)/page/year: 26,81,1972
Safety Information
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R43
[ Safety Phrases ]:
S36/S37