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Sodium p-toluenesulfonate

Names

[ CAS No. ]:
657-84-1

[ Name ]:
Sodium p-toluenesulfonate

[Synonym ]:
EINECS 211-522-5
MFCD00064388
Sodium p-toluenesulfonate

Chemical & Physical Properties

[ Density]:
1.55 g/cm3 (20℃)

[ Boiling Point ]:
140ºC at 20 MM HG

[ Melting Point ]:
>300°C

[ Molecular Formula ]:
C7H7NaO3S

[ Molecular Weight ]:
194.18

[ Flash Point ]:
500ºC

[ PSA ]:
62.75000

[ LogP ]:
2.32250

[ Vapour Pressure ]:
<1 hPa (20 °C)

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XT7350000
CHEMICAL NAME :
p-Toluenesulfonic acid, sodium salt
CAS REGISTRY NUMBER :
657-84-1
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C7-H7-O3-S.Na
MOLECULAR WEIGHT :
194.19
WISWESSER LINE NOTATION :
WSO&R D1 &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 14,536,1959 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83157 No. of Facilities: 69 (estimated) No. of Industries: 3 No. of Occupations: 10 No. of Employees: 1954 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83157 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1358 (estimated) No. of Female Employees: 956 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
XT7350000

[ HS Code ]:
29041000

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2904100000

[ Summary ]:
2904100000 derivatives containing only sulpho groups, their salts and ethyl esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Supported p-toluenesulfonic acid as a highly robust and eco-friendly isocyanide scavenger.

ACS Comb. Sci. 13(1) , 89-95, (2011)

We document here the use of polymer-supported p-toluenesulfonic acid as a highly effective, robust, economical and eco-friendly isocyanide scavenger. The herein described strategy circumvent the inten...

The transporter-opsin-G protein-coupled receptor (TOG) superfamily.

FEBS J. 280(22) , 5780-800, (2013)

Visual rhodopsins are recognized members of the large and diverse family of G protein-coupled receptors (GPCRs), but their evolutionary origin and relationships to other proteins are not known. In a p...

Coumarin–trioxane hybrids: Synthesis and evaluation as a new class of antimalarial scaffolds

Bioorg. Med. Chem. Lett. 22(12) , 3926-30, (2012)

A series of novel coumarin–trioxane hybrids were synthesized and evaluated for antimalarial activity.


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