AcBut

Names

[ Name ]:
AcBut

[Synonym ]:
4-(4-acetyl-phenoxy)butanoic acid
4-(p-acetylphenoxy)butyric acid
4-(4-Acetyl-phenoxy)-butyric acid
4-(4-Acetylphenyloxy)butyric acid

Biological Activity

[Description]:

AcBut is a cleavable Ozogamicin linker used in the synthesis of Ozogamicin, a drug-linker conjugate for ADC[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[References]

[1]. Beck A, et al. Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future. Expert Rev Proteomics. 2019;16(4):337-362.

Chemical & Physical Properties

[ Density]:
1.175±0.06 g/cm3(Predicted)

[ Boiling Point ]:
426.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₄O₄

[ Molecular Weight ]:
222.23700

[ Flash Point ]:
166.6ºC

[ Exact Mass ]:
222.08900

[ PSA ]:
63.60000

[ LogP ]:
2.13280

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

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