2-(2,4-Difluorophenyl)acetonitrile

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
216.1±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C₈H₅F₂N

[ Molecular Weight ]:
153.129

[ Flash Point ]:
93.3±0.0 °C

[ Exact Mass ]:
153.039001

[ PSA ]:
23.79000

[ LogP ]:
1.59

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.487

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36/37

[ RIDADR ]:
3276

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2926909090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Synthesis of novel inhibitors of the HIV-1 protease: difunctional enols of simple N-protected amino acids.

Bioorg. Med. Chem. 2(5) , 343-55, (1994)

A series of enol HIV-1 protease inhibitors which show competitive inhibition and the structure-activity relationship study which led to the design of these compounds are reported. By systematically mo...

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