m-PEG7-thiol

Names

[ Name ]:
m-PEG7-thiol

[Synonym ]:
O-(2-Mercaptoethyl)-O inverted exclamation marka-methyl-hexa(ethylene glycol)
AmbotzPEG1167
mPEG thiol
2,5,8,11,14,17,20-HEPTAOXADOCOSANE-22-THIOL
O-(2-Mercaptoethyl)-O'-methyl-hexa(ethylene glycol)

Biological Activity

[Description]:

m-PEG7-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Chemical & Physical Properties

[ Density]:
1.065

[ Molecular Formula ]:
C₁₅H₃₂O₇S

[ Molecular Weight ]:
356.47500

[ Exact Mass ]:
356.18700

[ PSA ]:
103.41000

[ LogP ]:
0.66220

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Enhanced thermal stability of silica-coated gold nanorods for photoacoustic imaging and image-guided therapy.

Opt. Express 18 , 8867-78, (2010)

Photothermal stability and, therefore, consistency of both optical absorption and photoacoustic response of the plasmonic nanoabsorbers is critical for successful photoacoustic image-guided phototherm...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.