L-Quebrachitol

Names

[ CAS No. ]:
642-38-6

[ Name ]:
L-Quebrachitol

[Synonym ]:
MFCD00021405
1L-2-O-METHYL-CHIRO-INOSITOL
2-o-methyl-l-inositol
1,2,3,4,5-Cyclohexanepentol, 6-methoxy-, (1α,2β,3α,4α,5β,6β)-
3-O-METHYL-L-CHIRO-INOSITOL
2-O-METHYL-L-CHIRO-INOSITOL
(1R,2S,3S,4S,5R,6R)-6-Methoxy-1,2,3,4,5-cyclohexanepentol
Quebrachitol
L-Quebrachitol
L-chiro-Inositol,2-O-methyl
(1R,2S,3S,4S,5R,6R)-6-Methoxycyclohexane-1,2,3,4,5-pentol
Quebrachitol, L-
QINGYANGSHENGENIN (RG)

Biological Activity

[Description]:

L-Quebrachitol is a natural product isolated from many plants, promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway[1].

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> Wnt

Research Areas >> Metabolic Disease

[References]

[1]. Yodthong T, et al. l-Quebrachitol Promotes the Proliferation, Differentiation, and Mineralization of MC3T3-E1 Cells: Involvement of the BMP-2/Runx2/MAPK/Wnt/β-Catenin Signaling Pathway. Molecules. 2018 Nov 26;23(12).

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
317.2±42.0 °C at 760 mmHg

[ Melting Point ]:
189 - 192ºC

[ Molecular Formula ]:
C₇H₁₄O₆

[ Molecular Weight ]:
194.182

[ Flash Point ]:
145.6±27.9 °C

[ Exact Mass ]:
194.079041

[ PSA ]:
110.38000

[ LogP ]:
-0.74

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.588

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S24/25

[ HS Code ]:
2909499000

Customs

[ HS Code ]: 2909499000

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%