Alloimperatorin

Names

[ CAS No. ]:
642-05-7

[ Name ]:
Alloimperatorin

[Synonym ]:
Prangenidin
Alloimperatorin
8-Hydroxy-5-isopentyl-6,7:4',5'-furocumarin

Biological Activity

[Description]:

Alloimperatorin (Prangenidin), a coumarin compound, is extracted from Angelica dahurica. Alloimperatorin (Prangenidin) has antitumor activity[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Chen Q, et al. Supercritical fluid extraction for identification and determination of volatile metabolites from Angelica dahurica by GC-MS. J Sep Sci. 2008 Oct;31(18):3218-24.

[2]. Li, H, et al. Alloimperatorin and Its Epoxide Derivative Exhibit in Vitro Antitumor Activity in HL-60 Acute Myeloid Leukemia Cancer Cells via Inducing Apoptosis, Cell Cycle Disruption and Inhibition of Cell Migration. Bangladesh Journal of Pharmacology, Vol. 11, no. 1, Jan. 2016, pp. 194-9.

Chemical & Physical Properties

[ Density]:
1.298g/cm3

[ Boiling Point ]:
476.1ºC at 760 mmHg

[ Melting Point ]:
224-225ºC

[ Molecular Formula ]:
C₁₆H₁₄O₄

[ Molecular Weight ]:
270.28000

[ Flash Point ]:
241.8ºC

[ Exact Mass ]:
270.08900

[ PSA ]:
63.58000

[ LogP ]:
3.75350

[ Index of Refraction ]:
1.641

[ Storage condition ]:
2-8℃

Safety Information

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%