4-chloro-N-(2-methylindol-1-yl)-3-sulfamoylbenzamide
Names
[ CAS No. ]:
63968-75-2
[ Name ]:
4-chloro-N-(2-methylindol-1-yl)-3-sulfamoylbenzamide
[Synonym ]:
N-(3-sulfamyl-4-chlorobenzamido)-2-methylindole
4-Chloro-N-(2-methyl-1-indolyl)-3-sulfamoylbenzamide
Benzamide,3-(aminosulfonyl)-4-chloro-N-(2-methyl-1H-indol-1-yl)
BENZAMIDE,4-CHLORO-N-(2-METHYL-1-INDOLYL)-3-SULFAMOYL
Dehydroindapamide
Indapamide Impurity 2
Chemical & Physical Properties
[ Density]:
1.49g/cm3
[ Melting Point ]:
255-257℃
[ Molecular Formula ]:
C16H14ClN3O3S
[ Molecular Weight ]:
363.81900
[ Exact Mass ]:
363.04400
[ PSA ]:
102.57000
[ LogP ]:
4.48850
[ Index of Refraction ]:
1.687
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CV2451500
- CHEMICAL NAME :
- Benzamide, 4-chloro-N-(2-methyl-1-indolyl)-3-sulfamoyl-
- CAS REGISTRY NUMBER :
- 63968-75-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C16-H14-Cl-N3-O3-S
- MOLECULAR WEIGHT :
- 363.84
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,2275,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 620 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,2275,1982
Safety Information
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2935009090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2935009090
[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%