4-[N-(2-Thiazolyl)sulfamoyl]-2-(anilinocarbonyl)benzoic acid sodium salt
Names
[ CAS No. ]:
63868-70-2
[ Name ]:
4-[N-(2-Thiazolyl)sulfamoyl]-2-(anilinocarbonyl)benzoic acid sodium salt
[Synonym ]:
Phthalanilic acid,4'-(2-thiazolylsulfamoyl)-,sodium salt
Phthalylsulfathiazole,sodium salt
85-73-4 (Parent)
2-(N(sup 4)-Phthalylsulfanilamido)thiazole sodium salt
Sodium phthalylsulfathiazole
Chemical & Physical Properties
[ Molecular Formula ]:
C17H12N3NaO5S2
[ Molecular Weight ]:
425.41400
[ Exact Mass ]:
425.01200
[ PSA ]:
164.91000
[ LogP ]:
2.78650
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TH8750000
- CHEMICAL NAME :
- Phthalanilic acid, 4'-(2-thiazolylsulfamoyl)-, sodium salt
- CAS REGISTRY NUMBER :
- 63868-70-2
- LAST UPDATED :
- 199607
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C17-H12-N3-O5-S2.Na
- MOLECULAR WEIGHT :
- 425.43
- WISWESSER LINE NOTATION :
- T5N CSJ BMSWR DMVR BVQ &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 81,116,1944 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 6 gm/kg/6D-I
- TOXIC EFFECTS :
- Liver - other changes Kidney, Ureter, Bladder - other changes Related to Chronic Data - death
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 81,116,1944