4-nitrobenzhydrazide

Names

[ CAS No. ]:
636-97-5

[ Name ]:
4-nitrobenzhydrazide

[Synonym ]:
EINECS 211-271-1
MFCD00007604
4-nitrobenzhydrazide

Chemical & Physical Properties

[ Density]:
1.406 g/cm3

[ Melting Point ]:
210-214 °C

[ Molecular Formula ]:
C₇H₇N₃O₃

[ Molecular Weight ]:
181.14900

[ Exact Mass ]:
181.04900

[ PSA ]:
100.94000

[ LogP ]:
1.81270

[ Index of Refraction ]:
1.621

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DH5670000

CHEMICAL NAME :: Benzoic acid, p-nitro-, hydrazide

CAS REGISTRY NUMBER :: 636-97-5

BEILSTEIN REFERENCE NO. :: 0519882

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H7-N3-O3

MOLECULAR WEIGHT :: 181.17

WISWESSER LINE NOTATION :: ZNUYQR DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00861

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S36/37/39-S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
DH5670000

[ HS Code ]:
2928000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Development and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometry method for determination of isoniazid in human plasma.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 877(3) , 285-90, (2009)

An LC-MS/MS method for the determination of isoniazid in human plasma was developed and validated. Human plasma aliquots of 100 microL were used for analysis. The assay used nialamide as the internal ...