Bruceoside A

Names

[ CAS No. ]:
63306-30-9

[ Name ]:
Bruceoside A

[Synonym ]:
bruceoside-A
Bruceosid-A
Bruceosid A

Biological Activity

[Description]:

Bruceoside A, an abundant quassinoid glycoside in Fructus Bruceae, possesses anti-cancer activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vivo]

Bruceoside A could be transformed into the potent anticancer component brusatol in vivo, rather than its direct deglycosylated metabolite bruceosin[1]. Animal Model: Male ICR mice weighing 25.0 ± 5.0 g[1]. Dosage: 22.5 mg/kg. Administration: Intragastrically administrated. Result: Reached its highest levels in three hours with a half-life value of 3.99 h.

[References]

[1]. Yuan Xu, et al. Pharmacokinetic study on bruceoside A revealed the potential role of quassinoid glycosides for the anticancer properties of Fructus Bruceae. J Pharm Biomed Anal. 2019 Jun 5;170:264-272.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₄₂O₁₆

[ Molecular Weight ]:
682.66600

[ Exact Mass ]:
682.24700

[ PSA ]:
245.04000

Precursor & DownStream

Precursor

DownStream

Related Compounds

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