4-Nitrobenzenesulfonamide
Names
[ CAS No. ]:
6325-93-5
[ Name ]:
4-Nitrobenzenesulfonamide
[Synonym ]:
4-Nitrobenzolesulfamide
4-Nitrobenzenesulphonamide
Benzenesulfonamide,p-nitro
EINECS 228-691-6
Benzenesulfonamide,4-nitro
p-Nitrophenylsulfonamide
4-Nitro-benzenesulfonamide
MFCD00007937
p-Nitrobenzene sulphonamide
4-nitrophenylsulfonamide
p-Nitrobenzenesulfonamide
p-nosyl-NH2
Chemical & Physical Properties
[ Density]:
1.552 g/cm3
[ Boiling Point ]:
417.8ºC at 760 mmHg
[ Melting Point ]:
178-180 °C(lit.)
[ Molecular Formula ]:
C6H6N2O4S
[ Molecular Weight ]:
202.18800
[ Flash Point ]:
206.5ºC
[ Exact Mass ]:
202.00500
[ PSA ]:
114.36000
[ LogP ]:
2.54650
[ Index of Refraction ]:
1.611
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DB2975000
- CHEMICAL NAME :
- Benzenesulfonamide, p-nitro-
- CAS REGISTRY NUMBER :
- 6325-93-5
- BEILSTEIN REFERENCE NO. :
- 2214218
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C6-H6-N2-O4-S
- MOLECULAR WEIGHT :
- 202.20
- WISWESSER LINE NOTATION :
- ZSWR DNW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,34,1953
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
S26-S37/39-S36/37/39-S22
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
DB2975000
[ HS Code ]:
2935009090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2935009090
[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%
Articles
ChemBioChem. 16(5) , 811-8, (2015)
Nitroreductases (NRs) and ene-reductases (ERs) both utilize flavin mononucleotide cofactors but catalyze distinct reactions. NRs reduce nitroaromatics, whereas ERs reduce unsaturated C=C double bonds,...
Copper (I)-catalyzed asymmetric alkene aziridination mediated by PhI (OAc)< sub> 2</sub>: a facile one-pot procedure. Kwong HL, et al.Tetrahedron Lett. 45(20) , 3965-3968, (2004)
The 1: 2 and 1: 1 molecular complexes of N,N'-dibenzyl-4, 13-diaza-18-crown-6 with 4-nitrobenzenesulfonamide and dithiooxamide. Fonari MS, et al.
J. Mol. Struct. 794(1) , 110-114, (2006)