(8S,9S,13S,14S,17S)-17-ethyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
Names
[ CAS No. ]:
6318-07-6
[ Name ]:
(8S,9S,13S,14S,17S)-17-ethyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
[Synonym ]:
17-Ethynylestriol
17-ETHYNYLESTRADIOL
17a-Ethynylestriol)
Chemical & Physical Properties
[ Density]:
1.11g/cm3
[ Boiling Point ]:
441.9ºC at 760 mmHg
[ Molecular Formula ]:
C20H30O2
[ Molecular Weight ]:
302.45100
[ Flash Point ]:
188.4ºC
[ Exact Mass ]:
302.22500
[ PSA ]:
37.30000
[ LogP ]:
4.41340
[ Index of Refraction ]:
1.555
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RC8961210
- CHEMICAL NAME :
- 19-Nor-17-alpha-pregn-5(10)-en-3-one, 17-hydroxy-
- CAS REGISTRY NUMBER :
- 6318-07-6
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H30-O2
- MOLECULAR WEIGHT :
- 302.50
- WISWESSER LINE NOTATION :
- L E5 B666 OV AU- MTJ E1 FQ F2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- DOSE :
- 150 mg/kg
- SEX/DURATION :
- female 30 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
- REFERENCE :
- RPHRA6 Recent Progress In Hormone Research. Proceedings of the Laurentian Hormone Conference. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1947- Volume(issue)/page/year: 20,395,1964
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 350 ug/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- 85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press, 1965 Volume(issue)/page/year: -,57,1965
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 1 mg/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- 13OPAL "Control of Ovulation, Proceedings of the Conference, Dedham, MA, 1960," Villee, C.A., ed., Oxford, UK, Pergamon Press Ltd., 1961 Volume(issue)/page/year: -,37,1961