Senkyunolide

Names

[ Name ]:
Senkyunolide

[Synonym ]:
(3S)-3-Butyl-4,5-dihydro-2-benzofuran-1(3H)-one
1(3H)-Isobenzofuranone, 3-butyl-4,5-dihydro-, (3S)-
1(3H)-Isobenzofuranone, 3-butyl-4,5-dihydro-, (S)-

Biological Activity

[Description]:

Senkyunolide A, isolated from Ligusticum chuanxiong Hort, has cytoprotective and antiproliferative activities. Anti-tumor activity[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Dalei Zhang, et al. Separation and Purification of Z Ligustilide and Senkyunolide A from Ligusticum chuanxiong Hort. with Supercritical Fluid Extraction and High‐Speed Counter‐Current Chromatography. Separation Science and Technology, 41: 3397-3408, 2006.

[2]. Kan WL, et al. Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells. J Ethnopharmacol. 2008 Oct 30;120(1):36-43.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
368.1±11.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₆O₂

[ Molecular Weight ]:
192.254

[ Flash Point ]:
154.2±16.7 °C

[ Exact Mass ]:
192.115036

[ PSA ]:
26.30000

[ LogP ]:
2.48

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.521

[ Storage condition ]:
2-8℃

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2932209090

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%