Tinazoline

Names

[ Name ]:
Tinazoline

[Synonym ]:
3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-benzo[d]isoxazole,monohydrochloride
3-(2-Imidazolin-2-yl)methyl-1,2-benzisoxazole hydrochloride
3-(2-imidazolin-2-ylthio)-indole
3-(2-Imidazolin-2-ylthio)-indol
3-(4,5-dihydro-1H-imidazol-2-ylsulfanyl)-indole

Biological Activity

[Description]:

Tinazoline, imidazole derivative, is a vasoconstrictor. Tinazoline can as nasal decongestant for the research of common cold[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Nagarajan K, et al. Structure activity relations among cyclic & acyclic S-(3-indolyl) isothioureas-development of a potent vasoconstrictor, tinazoline, 3-(2-imidazolin-2-yl-thio)indole. Indian J Exp Biol. 1981 Dec;19(12):1150-3.

Chemical & Physical Properties

[ Density]:
1.42g/cm3

[ Boiling Point ]:
437.6ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₁N₃S

[ Molecular Weight ]:
217.29000

[ Flash Point ]:
218.4ºC

[ Exact Mass ]:
217.06700

[ PSA ]:
65.48000

[ LogP ]:
1.98360

[ Index of Refraction ]:
1.755

Tinazoline

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Related Compounds