N,N-Diethyl-1,4-benzenediamine sulfate (1:1)
Names
[ CAS No. ]:
6283-63-2
[ Name ]:
N,N-Diethyl-1,4-benzenediamine sulfate (1:1)
[Synonym ]:
sulfate salt of N,N-diethyl-p-phenylenediamine
1,4-Benzenediamine, N,N-diethyl-, sulfate (1:1)
P-AMINO-N,N-DIETHYLANILINE SULFATE
N,N-Diethyl-p-phenylen-diamin-hydrogensulfat
DPD TABLET
sirann,n-diethyl-p-fenylendiaminu
EINECS 228-500-6
N,N-Diethyl-1,4-benzenediamine sulfate (1:1)
MFCD00012993
DPD REAGENT
N,N-Diethylbenzene-1,4-diamine sulfate (1:1)
4-amino-N,N-diethylaniline sulphate
4-AMINO-N,N-DIETHYLANILINE SULFATE
P-AMINODIETHYLANILINE SULFATE
4-N,N-Diethylaminoanilin Hydrogensulfat
CD1 SULFATE
N,N-diethylbenzene-1,4-diamine sulfate
DPD SULPHATE
diethylphenylenediaminesulfate
Chemical & Physical Properties
[ Boiling Point ]:
274 - 275
[ Melting Point ]:
184-186 °C(lit.)
[ Molecular Formula ]:
C10H18N2O4S
[ Molecular Weight ]:
262.326
[ Exact Mass ]:
262.098724
[ PSA ]:
112.24000
[ LogP ]:
3.12420
[ Water Solubility ]:
H2O: 0.1 g/mL, clear
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SS9625000
- CAS REGISTRY NUMBER :
- 6283-63-2
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C10-H16-N2.H2-O4-S
- MOLECULAR WEIGHT :
- 262.36
- WISWESSER LINE NOTATION :
- ZR DN2&2 &S-O4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy)
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy)
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intratracheal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - ataxia Behavioral - muscle contraction or spasticity
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - rigidity (including catalepsy) Blood - methemoglobinemia-carboxyhemoglobin
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - rigidity (including catalepsy) Blood - methemoglobinemia-carboxyhemoglobin
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 318 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - ataxia Behavioral - muscle contraction or spasticity
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 560 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - ataxia Behavioral - muscle contraction or spasticity
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10920 ug/kg/26W-I
- TOXIC EFFECTS :
- Liver - other changes Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2745 mg/kg/61D-I
- TOXIC EFFECTS :
- Blood - pigmented or nucleated red blood cells Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 244 mg/kg/61D-I
- TOXIC EFFECTS :
- Brain and Coverings - changes in circulation (hemorrhage, thrombosis, etc.) Liver - hepatitis (hepatocellular necrosis), zonal Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 36 mg/kg
- SEX/DURATION :
- male 60 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 8 mg/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 238,1,1990
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S28-S45
[ RIDADR ]:
2811
[ WGK Germany ]:
3
[ RTECS ]:
SS9625000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
29215190
Customs
[ HS Code ]: 29215190
Articles
Water Res. 43(13) , 3308-18, (2009)
Chlorination of indoor swimming pools is practiced for disinfection and oxidation of reduced compounds that are introduced to water by swimmers. However, there is growing concern associated with forma...
Use of N, N-diethyl-p-phenylenediamine sulphate for the spectrophotometric determination of some phenolic and amine drugs.Acta. Pharm. 60(2) , 217-27, (2010)
Spectrophotometric methods are proposed for the determination of drugs containing a phenol group [salbutamol sulphate (SLB), ritodrine hydrochloride (RTD), isoxsuprine hydrochloride (IXP)] and drugs c...
Differentiation of Salmonella typhi using resistotyping.J. Appl. Bacteriol. 54(2) , 171-6, (1983)