adipamide
Names
[ CAS No. ]:
628-94-4
[ Name ]:
adipamide
[Synonym ]:
adipic acid bisamide
HSDB 5510
Adipic acid amide
Adipic acid diamide
CCRIS 5883
Adipic diamide
Adipamide
1,4-Butanedicarboxamide
Adipinsaeurediamid
MFCD00008045
EINECS 211-062-5
Chemical & Physical Properties
[ Density]:
1.18g/cm3
[ Boiling Point ]:
412.4ºC at 760 mmHg
[ Melting Point ]:
226-229 °C(lit.)
[ Molecular Formula ]:
C6H12N2O2
[ Molecular Weight ]:
144.17200
[ Flash Point ]:
203.2ºC
[ Exact Mass ]:
144.09000
[ PSA ]:
86.18000
[ LogP ]:
0.91800
[ Index of Refraction ]:
1.48
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AU7800000
- CHEMICAL NAME :
- Adipamide
- CAS REGISTRY NUMBER :
- 628-94-4
- BEILSTEIN REFERENCE NO. :
- 1762331
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C6-H12-N2-O2
- MOLECULAR WEIGHT :
- 144.20
- WISWESSER LINE NOTATION :
- ZV4VZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6 gm/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 34,1196,1940 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1270 mg/kg/1Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
- REFERENCE :
- JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 3(5-6),149,1980
Safety Information
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
AU7800000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Environ. Pathol. Toxicol. 3(5-6) , 149-70, (1980)
As a part of the National Cancer Institute's effort to screen environmental and occupational chemicals for chronic toxicity and carcinogenicity, the amides acetamide, hexanamide, adipamide, urea, and ...
The preparation of nylon-tube-supported hexokinase and glucose 6-phosphate dehydrogenase and the use of the co-immobilized enzymes in the automated determination of glucose.Biochem. J. 147(3) , 593-603, (1975)
Triethyloxonium tetrafluoroborate was used to O-alkylate nylon-tube thus producing the imidate salt of the nylon which was further made to react with 1,6-diaminohexane. 2. Hexokinase (EC 2.7.1.1) and ...
Development of biomimetic nano-hydroxyapatite/poly(hexamethylene adipamide) composites.Biomaterials 23(24) , 4787-91, (2002)
In this study, acicular nano-hydroxyapatite (n-HA) was used to make a new biomimetic composite with polyamide (poly hexamethylene adipamide) by a unique technique. The physical and chemical characteri...