Stearic acid-d1

Names

[ Name ]:
Stearic acid-d1

[Synonym ]:
12-deoxyphorbol-13-isobutyrate-20-acetate
12-deoxyphorbol-13-isobutyrate
12-Desoxyphorbol 13-isobutyrate
12-deuterio-octadecanoic acid

Biological Activity

[Description]:

Stearic acid-d1 is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Shen MC et al. Dietary stearic acid leads to a reduction of visceral adipose tissue in athymic nude mice. PLoS One. 2014 Sep 15;9(9):e104083.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₃₅DO₂

[ Molecular Weight ]:
285.48

[ Exact Mass ]:
285.27800

[ PSA ]:
37.30000

[ LogP ]:
6.33250

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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