Ioxynic acid
Names
[ CAS No. ]:
618-76-8
[ Name ]:
Ioxynic acid
[Synonym ]:
4-carboxy-2,6-di-iodophenol
Ioxynil acid
p-hydroxy-3,5-diiodobenzoic acid
4-hydroxy-3,5-diiodo-benzoic acid
3,5-Diiod-4-hydroxy-benzoesaeure
3,5-Diiodo-4-hydroxybenzoic acid
EINECS 210-562-0
MFCD00016532
Benzoic acid,4-hydroxy-3,5-diiodo
4-Hydroxy-3,5-dijod-benzoesaeure
Chemical & Physical Properties
[ Density]:
2.697g/cm3
[ Boiling Point ]:
346.4ºC at 760 mmHg
[ Melting Point ]:
275°C (dec.)
[ Molecular Formula ]:
C7H4I2O3
[ Molecular Weight ]:
389.91400
[ Flash Point ]:
163.3ºC
[ Exact Mass ]:
389.82500
[ PSA ]:
57.53000
[ LogP ]:
2.29960
[ Index of Refraction ]:
1.784
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DG8597500
- CHEMICAL NAME :
- Benzoic acid, 3,5-diiodo-4-hydroxy-
- CAS REGISTRY NUMBER :
- 618-76-8
- BEILSTEIN REFERENCE NO. :
- 2212145
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C7-H4-I2-O3
- MOLECULAR WEIGHT :
- 389.91
- WISWESSER LINE NOTATION :
- QVR DQ CI EI
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,20,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 43,495,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 2,213,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOCEAH Journal of Organic Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1936- Volume(issue)/page/year: 22,1686,1957
Safety Information
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RTECS ]:
DG8597500
[ HS Code ]:
2918290000
Synthetic Route
Customs
[ HS Code ]: 2918290000
[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%