Phenylbutanolamine hydrochloride
Names
[ CAS No. ]:
6170-27-0
[ Name ]:
Phenylbutanolamine hydrochloride
[Synonym ]:
Nor-homoephedrine
1-hydroxy-1-phenylbutan-2-aminium chloride
Phenylbutanolamine hydrochloride
(1-hydroxy-1-phenylbutan-2-yl)azanium chloride
(1RS,2SR)-2-amino-1-phenyl-butan-1-ol,hydrochloride
(+/-)-(1R,2S)-2-amino-1-phenyl-1-butanol hydrochloride
(1RS,2SR)-2-Amino-1-phenyl-butan-1-ol,Hydrochlorid
Chemical & Physical Properties
[ Boiling Point ]:
302.4ºC at 760 mmHg
[ Molecular Formula ]:
C10H16ClNO
[ Molecular Weight ]:
201.69300
[ Flash Point ]:
136.7ºC
[ Exact Mass ]:
201.09200
[ PSA ]:
46.25000
[ LogP ]:
2.95960
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DN8050000
- CHEMICAL NAME :
- Benzyl alcohol, alpha-(1-aminopropyl)-, hydrochloride, (+-)-
- CAS REGISTRY NUMBER :
- 6170-27-0
- LAST UPDATED :
- 199509
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C10-H15-N-O.Cl-H
- MOLECULAR WEIGHT :
- 201.72
- WISWESSER LINE NOTATION :
- ZY2&YQR &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Vascular - BP elevation not characterized in autonomic section
- REFERENCE :
- JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 52,3317,1930
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 130 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- BANMAC Bulletin de l'Academie Nationale de Medicine (Paris). (Imprimeries Reunies de Chambray, 226, route d'Apremont, F-73490 La Ravoire, France) V.1- 1836- Volume(issue)/page/year: 98,101,1927