Methyl α-D-mannopyranoside

Names

[ CAS No. ]:
617-04-9

[ Name ]:
Methyl α-D-mannopyranoside

[Synonym ]:
MFCD00063262
EINECS 210-502-3
Methyl α-D-mannopyranoside
α-D-Mannopyranoside, methyl
Methyl .α.-D-mannopyranoside
Methyl a-D-Mannopyranoside

Biological Activity

[Description]:

Methyl α-D-mannopyranoside could target macrophages in anti-tuberculosis inhalation therapy[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Maretti E, et, al. Surface engineering of Solid Lipid Nanoparticle assemblies by methyl α-d-mannopyranoside for the active targeting to macrophages in anti-tuberculosis inhalation therapy. Int J Pharm. 2017 Aug 7; 528(1-2):440-451.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
389.1±42.0 °C at 760 mmHg

[ Melting Point ]:
193-196ºC

[ Molecular Formula ]:
C₇H₁₄O₆

[ Molecular Weight ]:
194.182

[ Flash Point ]:
189.1±27.9 °C

[ Exact Mass ]:
194.079041

[ PSA ]:
99.38000

[ LogP ]:
-2.69

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.548

[ Storage condition ]:
Refrigerator

[ Water Solubility ]:
H2O: 0.1 g/mL, clear

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi,F

[ Risk Phrases ]:
10

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Articles

Synthesis of glycopeptide dendrimers, dimerization and affinity for Concanavalin A.

Bioorg. Med. Chem. 19 , 2879-87, (2011)

We described herein the synthesis of second generation glycopeptide dendrimers G2a-g presenting variable amino acids placed internally into the multivalent scaffold. The effect of such structural modu...

Redox-responsive and calcium-dependent switching of glycosyldisulfide interactions with Concanavalin A.

Bioorg. Med. Chem. Lett. 15 , 2707-10, (2005)

Glycosyldisulfides can interact efficiently with carbohydrate-binding entities. This has been shown for a range of thiosaccharide dimers when tested for their effects against the lectin Concanavalin A...

BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport.

Antimicrob. Agents Chemother. 51 , 4492-4, (2007)

BK virus is an important pathogen in kidney transplant recipients. In vitro studies demonstrated slight antiviral activity for chloroquine and nystatin. A sialic acid derivative, BTB11968, was identif...