2-Hydroxycinnamic acid
Names
[ CAS No. ]:
614-60-8
[ Name ]:
2-Hydroxycinnamic acid
[Synonym ]:
(2E)-3-(2-Hydroxyphenyl)-2-propenoic acid
(2E)-3-(2-Hydroxyphenyl)acrylic acid
(E)-o-coumaric acid
trans-2-coumaric acid
o-Coumaric acid
(E)-3-(2-Hydroxyphenyl)-2-propenoic acid
Cinnamic acid, o-hydroxy-, (E)-
Coumaric acid
2-Propenoic acid, 3-(2-hydroxyphenyl)-, (E)-
o-Hydroxy-trans-cinnamic acid
2-Hydroxycinnamic acid, (E)-
QV1U1R BQ &&E or trans Form
(E)-3-(2-Hydroxyphenyl)acrylic acid
Cinnamic acid, o-hydroxy-
2-Propenoic acid, 3-(2-hydroxyphenyl)-, (2E)-
(2E)-3-(2-Hydroxyphenyl)prop-2-enoic acid
EINECS 210-386-4
trans-2-Hydroxycinnamic acid
trans-o-Coumaric Acid
trans-o-Hydroxycinnamic acid
o-Hydroxycinnamic acid
2-Hydroxycinnamic acid
(E)-2-Hydroxycinnamic acid
(E)-o-Hydroxycinnamic acid
(E)-3-(2-Hydroxyphenyl)prop-2-enoic acid
MFCD00004379
ortho-Hydroxycinnamic acid
Biological Activity
[Description]:
[Related Catalog]:
[Target]
HIV
[References]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
348.0±17.0 °C at 760 mmHg
[ Melting Point ]:
217ºC
[ Molecular Formula ]:
C9H8O3
[ Molecular Weight ]:
164.158
[ Flash Point ]:
178.5±17.4 °C
[ Exact Mass ]:
164.047348
[ PSA ]:
57.53000
[ LogP ]:
2.43
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.660
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GD9090000
- CHEMICAL NAME :
- Cinnamic acid, o-hydroxy-, (E)-
- CAS REGISTRY NUMBER :
- 614-60-8
- BEILSTEIN REFERENCE NO. :
- 1100900
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H8-O3
- MOLECULAR WEIGHT :
- 164.17
- WISWESSER LINE NOTATION :
- QV1U1R BQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02587
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H315-H319-H335
[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S24/25-S36
[ RIDADR ]:
UN 2811
[ WGK Germany ]:
3
[ RTECS ]:
GD9090000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Pharm. Biol. 53(6) , 800-6, (2015)
The number of multidrug resistant (MDR) microorganisms is increasing and the antimicrobial resistance expressed by these pathogens is generating a rising global health crisis. In fact, there are only ...
Soluble and cell wall-bound phenolic acids and ferulic acid dehydrodimers in rye flour and five bread model systems: insight into mechanisms of improved availability.J. Sci. Food Agric. 95(5) , 1103-15, (2015)
The bread-making process influences bread components, including phenolics that significantly contribute to its antioxidant properties. Five bread model systems made from different rye cultivars were i...
Effect of enzymatic pretreatment of various lignocellulosic substrates on production of phenolic compounds and biomethane potential.Bioresour. Technol. 192 , 696-702, (2015)
Pretreatment of lignocellulosic biomass is necessary to enhance the hydrolysis, which is the rate-limiting step in biogas production. Laccase and versatile peroxidase are enzymes known to degrade lign...