3,3'-Dichlorobenzidine 2HCl
Names
[ CAS No. ]:
612-83-9
[ Name ]:
3,3'-Dichlorobenzidine 2HCl
[Synonym ]:
3,3'-Dichlorobenzidine 2HCl
3,3'-Dichlorobiphenyl-4,4'-diamine dihydrochloride
Benzidine,3,3'-dichloro-,dihydrochloride
[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dichloro-, hydrochloride (1:2)
[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dichloro-, dihydrochloride
3,3'-Dichloro-4,4'-biphenyldiamine dihydrochloride
3,3'-DICHLOROBENZIDINE DIHYDROCHLORIDE
MFCD00040388
EINECS 210-323-0
Chemical & Physical Properties
[ Boiling Point ]:
385ºC at 760 mmHg
[ Melting Point ]:
132~137℃
[ Molecular Formula ]:
C12H12Cl4N2
[ Molecular Weight ]:
326.049
[ Exact Mass ]:
323.975464
[ PSA ]:
52.04000
[ LogP ]:
6.59120
[ Stability ]:
Stable, but may be air or light sensitive. Incompatible with strong oxidizing agents.
[ Water Solubility ]:
<0.1 g/100 mL at 21.5 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DD0550000
- CHEMICAL NAME :
- Benzidine, 3,3'-dichloro-, dihydrochloride
- CAS REGISTRY NUMBER :
- 612-83-9
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C12-H10-Cl2-N2.2Cl-H
- MOLECULAR WEIGHT :
- 326.06
- WISWESSER LINE NOTATION :
- ZR BG D- 2 &GH &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3820 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 10 ug/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5(Suppl 1),3,1983 *** U.S. STANDARDS AND REGULATIONS *** OSHA-cancer suspect agent CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1007,1987
Safety Information
[ Symbol ]:
GHS07, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H312-H317-H350-H410
[ Precautionary Statements ]:
P201-P280-P308 + P313
[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R45;R21;R43;R50/53
[ Safety Phrases ]:
S53-S45-S60-S61
[ RIDADR ]:
UN 3077 9/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
DD0550000
[ HS Code ]:
2921590090
Customs
[ HS Code ]: 2921590090
[ Summary ]:
2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
J. Environ. Pathol. Toxicol. Oncol. 1 , 475-490, (1978)
Six female beagle dogs were given, by capsule, a daily oral dose of 100 mg of 3,3'-dichlorobenzidine (DCB), 3 times per week for 6 weeks, then 5 times per week continuously for periods up to 7.1 years...