BMS-561392

Names

[ Name ]:
BMS-561392

Biological Activity

[Description]:

BMS-561392 is a TNF alpha-converting enzyme (TACE) inhibitor. BMS-561392 is also an ADAM17 blocker. BMS-561392 can be used for research of inflammatory bowel disease[1][2].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. Kim ML, et al. Effects of TNFalpha-converting enzyme inhibition on amyloid beta production and APP processing in vitro and in vivo. J Neurosci. 2008 Nov 12;28(46):12052-61.

[2]. Vidal PM, et al. ADAM17 is a survival factor for microglial cells in vitro and in vivo after spinal cord injury in mice. Cell Death Dis. 2013 Dec 12;4(12):e954.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₃₂N₄O₄

[ Molecular Weight ]:
476.57

Related Compounds

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