1N1&VR
Names
[ CAS No. ]:
611-74-5
[ Name ]:
1N1&VR
[Synonym ]:
N,N-dimethylbutylbenzamide
1N1&VR
Dimethylbenzmide
NN-Dimethylbenzamide
Dimethylbenzamide
N,N-Dimethylbenzamide
EINECS 210-279-2
Benzamide,N,N-dimethyl
N,N-dimethyl benzamide
MFCD00008320
Benzamide, N,N-dimethyl-
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
256.1±9.0 °C at 760 mmHg
[ Melting Point ]:
43-45 °C(lit.)
[ Molecular Formula ]:
C9H11NO
[ Molecular Weight ]:
149.190
[ Flash Point ]:
111.9±9.9 °C
[ Exact Mass ]:
149.084061
[ PSA ]:
20.31000
[ LogP ]:
0.44
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.529
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CV4500000
- CHEMICAL NAME :
- Benzamide, N,N-dimethyl-
- CAS REGISTRY NUMBER :
- 611-74-5
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H11-N-O
- MOLECULAR WEIGHT :
- 149.21
- WISWESSER LINE NOTATION :
- 1N1&VR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 960 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 19,20,1971
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
CV4500000
[ HS Code ]:
2924299090
Synthetic Route
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Biochem. Pharmacol. 32(11) , 1773-81, (1983)
The stability of metabolically-generated N-(hydroxymethyl) compounds was investigated using a series of N-methylbenzamides as model substrates. N-(Hydroxymethyl)-benzamide was characterized as a major...
Hydrotropic polymer micelles as versatile vehicles for delivery of poorly water-soluble drugs.J. Control. Release 152(1) , 13-20, (2011)
Polymer micelles have been used widely for delivery of poorly water-soluble drugs. Such drug delivery, however, has been based primarily on hydrophobic interactions. For better drug loading and improv...
Hydrotropic solubilization of poorly water-soluble drugs.J. Pharm. Sci. 99(9) , 3953-65, (2010)
The solubilizing ability of two aromatic hydrotropes, N,N-diethylnicotinamide (DENA) and N,N-dimethylbenzamide (DMBA), was investigated using a set of 13 poorly soluble, structurally diverse drugs. Th...