2,4-Dichloronitrobenzene

Names

[ CAS No. ]:
611-06-3

[ Name ]:
2,4-Dichloronitrobenzene

[Synonym ]:
Nitro-2,4-dichlorobenzene
2,4-DCNB
1-Nitro-2,4-dichlorobenzene
1,3-DICHLORO-4-NITROBENZENE
MFCD00007071
1,3-Dichlor-4-nitrobenzol
4-Nitro-m-dichlorobenzene
2,4-dichloro-nitrobenzene
2,4-dichloro-1-nitro-benzen
EINECS 210-248-3
4-Dichloronitrobenzene
2,4-chloronitrobenzene
2,6-dichloro-3-nitrobenzene
2,4-DICHLORO-1-NITROBENZENE

Chemical & Physical Properties

[ Density]:
1.479

[ Boiling Point ]:
258 °C(lit.)

[ Melting Point ]:
29-32 °C(lit.)

[ Molecular Formula ]:
C₆H₃Cl₂NO₂

[ Molecular Weight ]:
192.00000

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
190.95400

[ PSA ]:
45.82000

[ LogP ]:
3.42480

[ Index of Refraction ]:
1.5512 (78.1ºC)

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.

[ Water Solubility ]:
188 mg/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ5420000

CHEMICAL NAME :: Benzene, 2,4-dichloro-1-nitro-

CAS REGISTRY NUMBER :: 611-06-3

BEILSTEIN REFERENCE NO. :: 1451655

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H3-Cl2-N-O2

MOLECULAR WEIGHT :: 192.00

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 3 ug/plate

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5(Suppl 1),3,1983

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R21/22;R43;R51/53

[ Safety Phrases ]:
S26-S36-S61-S36/37-S24

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
CZ5420000

[ Packaging Group ]:
III

[ Hazard Class ]:
9

[ HS Code ]:
29049085

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Control of the immune response to contact sensitizing chemicals by cutaneous antigen-presenting cells.

Br. J. Dermatol. 117(1) , 1-9, (1987)

The fate of 2,4-dinitrochlorobenzene, a potent contact sensitizing chemical, and 2,4-dichloronitrobenzene, a non-sensitizer, was compared following their application to the skin of BALB/c mice. Althou...

Contribution of caffeine and flavanols in the induction of hepatic Phase II activities by green tea.

Food Chem. Toxicol. 36(8) , 617-21, (1998)

Aqueous extracts of green tea, at concentrations of 2.5. 5.0 and 7.5%, were administered to rats as the sole drinking fluid for 4 weeks. Hepatic glutathione S-transferase (GST) activity, determined us...

Dose-response effects of lycopene on selected drug-metabolizing and antioxidant enzymes in the rat.

Cancer Lett. 154(2) , 201-10, (2000)

The administration of lycopene to female rats at doses ranging from 0.001 to 0.1 g/kg b.w. per day for 2 weeks was found to alter the drug-metabolizing capacity and antioxidant status of the exposed a...