10-Formyl-5,8-dideazafolic acid

Names

[ CAS No. ]:
61038-31-1

[ Name ]:
10-Formyl-5,8-dideazafolic acid

Biological Activity

[Description]:

10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Thymidylate Synthase

Research Areas >> Cancer

[Target]

thymidylate synthase[1]

[References]

[1]. Reddy MR, et, al. Calculation of solvation and binding free energy differences for folate-based inhibitors of the enzyme thymidylate synthase. J. Am. Chem. Soc. 1992, 114, 26, 10117-10122.

Chemical & Physical Properties

[ Density]:
1.54g/cm3

[ Molecular Formula ]:
C₂₂H₂₁N₅O₇

[ Molecular Weight ]:
467.43100

[ Exact Mass ]:
467.14400

[ PSA ]:
196.04000

[ LogP ]:
2.73640

[ Index of Refraction ]:
1.699

Related Compounds

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