Piperidine hydrochloride
Names
[ CAS No. ]:
6091-44-7
[ Name ]:
Piperidine hydrochloride
[Synonym ]:
piperidine hydrochloride
EINECS 228-033-8
Piperidine, hydrochloride (1:1)
Piperidine hydrochloride (1:1)
Piperidinhydrochlorid
MFCD00012770
Chemical & Physical Properties
[ Density]:
1,12 g/cm3
[ Boiling Point ]:
106.4ºC at 760 mmHg
[ Melting Point ]:
245-248 °C(lit.)
[ Molecular Formula ]:
C5H12ClN
[ Molecular Weight ]:
121.608
[ Flash Point ]:
>230 °F
[ Exact Mass ]:
121.065826
[ PSA ]:
16.61000
[ Vapour density ]:
2.94 (vs air)
[ Vapour Pressure ]:
63.6 mm Hg ( 37.8 °C)
[ Water Solubility ]:
soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TN0400000
- CHEMICAL NAME :
- Piperidine, hydrochloride
- CAS REGISTRY NUMBER :
- 6091-44-7
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C5-H11-N.Cl-H
- MOLECULAR WEIGHT :
- 121.63
- WISWESSER LINE NOTATION :
- T6NTJ &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 133 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,289,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 330 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 17,475,1967
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 657 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - other (direct) parasympathomimetic Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 50,199,1903
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 160 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 112,36,1957
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - other (direct) parasympathomimetic Cardiac - pulse rate Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 50,199,1903
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301
[ Precautionary Statements ]:
P301 + P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R23/24/25;R36/37/38
[ Safety Phrases ]:
S36/37/39-S45-S28A-S26
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
1
[ RTECS ]:
TN0400000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
29333200
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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