N,N,2-Trimethylaniline
Names
[ CAS No. ]:
609-72-3
[ Name ]:
N,N,2-Trimethylaniline
[Synonym ]:
MFCD00035789
2-(Dimethylamino)toluene
N,N,2-Trimethylaniline
N,N,2-Trimethylbenzenamine
EINECS 210-199-8
Benzenamine, N,N,2-trimethyl-
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
185.9±9.0 °C at 760 mmHg
[ Melting Point ]:
-61.3ºC
[ Molecular Formula ]:
C9H13N
[ Molecular Weight ]:
135.206
[ Flash Point ]:
72.6±11.7 °C
[ Exact Mass ]:
135.104797
[ PSA ]:
3.24000
[ LogP ]:
2.79
[ Vapour Pressure ]:
0.7±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.544
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XU5800000
- CHEMICAL NAME :
- o-Toluidine, N,N-dimethyl-
- CAS REGISTRY NUMBER :
- 609-72-3
- BEILSTEIN REFERENCE NO. :
- 2205144
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C9-H13-N
- MOLECULAR WEIGHT :
- 135.23
- WISWESSER LINE NOTATION :
- 1N1&R B1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 338 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AISFAR Archivio Italiano di Scienze Farmacologiche. (Modena, Italy) V.1-11, 1932-42; Series 2: V.1-3, 1948-50; Series 3: V.1-15, 1951-65. Discontinued. Volume(issue)/page/year: 1,284,1951
Safety Information
[ Symbol ]:
GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H311-H331-H373-H412
[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R23/24/25;R33;R52/53
[ Safety Phrases ]:
S23-S26-S36/37/39-S45-S61-S36/37-S28A
[ RIDADR ]:
UN 2810 6.1/PG 2
[ WGK Germany ]:
1
[ RTECS ]:
XU5800000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
2921430090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921430090
[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
J. Am. Chem. Soc. 82(1) , 40-45, (1960)
Effect of tetramethylethylenediamine on the metalation of o- and p-N,N-dimethyltoluidines with n-butyllithium. Deuteration and electrophilic condensation of intermediate lithioamines. Ludt RE, et al.
J. Org. Chem. 35(5) , 1288-96, (1970)
Photo-dynamics of roseoflavin and riboflavin in aqueous and organic solvents. Zirak P, et al.
Chem. Phys. 358(1) , 111-122, (2009)