Ethyl 2-Chloroacetoacetate
Names
[ CAS No. ]:
609-15-4
[ Name ]:
Ethyl 2-Chloroacetoacetate
[Synonym ]:
Butanoic acid, 2-chloro-3-oxo-, ethyl ester
Butanoic acid, 4-chloro-3-oxo-, ethyl ester
Butanoic acid, 4-chloro-3-oxo-ethylester
MFCD00009141
Acetoacetic acid, 2-chloro-, ethyl ester (8CI)
ETHYL 2-CHLORO-3-OXO-BUTANOATE
Ethyl 4-chloro-3-oxobutanoate
EINECS 210-180-4
Ethyl 2-Chloroacetoacetate
Ethyl α-chloroacetoacetate
2-Chloroacetoacetic acid ethyl ester
Ethyl 4-chloroacetoacetate
Ethyl 2-chloro-3-oxobutanoate
ethyl2-chloro-3-oxobutanoate
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
225.5±0.0 °C at 760 mmHg
[ Melting Point ]:
-80 °C
[ Molecular Formula ]:
C6H9ClO3
[ Molecular Weight ]:
164.587
[ Flash Point ]:
50.0±0.0 °C
[ Exact Mass ]:
164.024017
[ PSA ]:
43.37000
[ LogP ]:
1.66
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.434
[ Storage condition ]:
2~8 ℃
[ Water Solubility ]:
17 g/L (20 ºC)
MSDS
Safety Information
[ Symbol ]:
GHS02, GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H302-H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S16-S26-S36/37/39-S45-S61-S37/39
[ RIDADR ]:
UN 2920 8/PG 2
[ WGK Germany ]:
2
[ Packaging Group ]:
III
[ Hazard Class ]:
3.2
[ HS Code ]:
29183000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2918300090
[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
ChemBioChem. 5(1) , 87-92, (2004)
Saccharomyces cerevisiae reduces the beta-keto ester ethyl 2-chloroacetoacetate to the respective chiral cis- and trans-beta-hydroxy esters. In the course of chiral reduction, competing dehalogenation...
Analysis of inhibitors of the site-specific recombination reaction mediated by Tn3 resolvase.J. Mol. Biol. 206(2) , 295-304, (1989)
The Tn3-encoded resolvase protein promotes a site-specific recombination reaction between two directly repeated copies of the recombination site res. Several inhibitors that block this event in vitro ...
Synthesis and antiinflammatory activity of novel 2, 5-disubstituted thiophene derivatives. Badr SMI.Turk. J. Chem. 35(1) , 131-143, (2011)