Pentabromophenol
Names
[ CAS No. ]:
608-71-9
[ Name ]:
Pentabromophenol
[Synonym ]:
Pentabromophenol
Phenol, 2,3,4,5,6-pentabromo-
EINECS 210-167-3
2,3,4,5,6-pentabromophenol
MFCD00002147
Chemical & Physical Properties
[ Density]:
2.9±0.1 g/cm3
[ Boiling Point ]:
352.3±37.0 °C at 760 mmHg
[ Melting Point ]:
223-226 °C(lit.)
[ Molecular Formula ]:
C6HBr5O
[ Molecular Weight ]:
488.591
[ Flash Point ]:
166.9±26.5 °C
[ Exact Mass ]:
483.594391
[ PSA ]:
20.23000
[ LogP ]:
6.10
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.719
[ Stability ]:
Stable. Incompatible with strong oxidizing agents, strong bases.
[ Water Solubility ]:
Insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SM6125000
- CHEMICAL NAME :
- Phenol, pentabromo-
- CAS REGISTRY NUMBER :
- 608-71-9
- BEILSTEIN REFERENCE NO. :
- 1876757
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C6-H-Br5-O
- MOLECULAR WEIGHT :
- 488.62
- WISWESSER LINE NOTATION :
- QR BE CE DE EE FE
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,527,1986
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 5,288,1953
Safety Information
[ Symbol ]:
GHS06, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301 + H311 + H331-H315-H319-H335-H400
[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P305 + P351 + P338-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R23/24/25;R36/37/38;R50/53
[ Safety Phrases ]:
S26-S36/37-S45-S60-S61
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
SM6125000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2908199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2908199090
[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%
Articles
Anal. Bioanal. Chem 390(3) , 921-8, (2008)
X-ray absorption fine structure (EXAFS) spectroscopy spectra were collected for three brominated persistent pollutants: 6-bromo-2,4,5-trichlorophenol (BrTriClP), pentabromophenol (PentaBrP) and 3,3',5...
Structure of human transthyretin complexed with bromophenols: a new mode of binding.Acta Crystallogr. D Biol. Crystallogr. 56(Pt 9) , 1085-95, (2000)
The binding of two organohalogen substances, pentabromophenol (PBP) and 2,4,6-tribromophenol (TBP), to human transthyretin (TTR), a thyroid hormone transport protein, has been studied by in vitro comp...
Investigations on acute hepato- and nephrotoxicity of pentabromophenol.Int. J. Occup. Med. Environ. Health 8(3) , 245-54, (1995)
Pentabromophenol (PBP) was administered in a single or repeated doses to mice or in a single dose to rats. Slight changes were noted in the level of SGPT in mice serum and GSH in the liver, with a mor...