(S)-2-AMINO-4-(2-AMINO-3-HYDROXYPHENYL)-4-OXOBUTANOIC ACID
Names
[ CAS No. ]:
606-14-4
[ Name ]:
(S)-2-AMINO-4-(2-AMINO-3-HYDROXYPHENYL)-4-OXOBUTANOIC ACID
[Synonym ]:
rac 3-Hydroxy Kynurenine
(S)-2-Amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid
Paralysin II
REF DUPL: DL-3-Hydroxykynurenine
Chemical & Physical Properties
[ Density]:
1.461g/cm3
[ Boiling Point ]:
519.3ºC at 760 mmHg
[ Molecular Formula ]:
C10H12N2O4
[ Molecular Weight ]:
224.21300
[ Flash Point ]:
267.9ºC
[ Exact Mass ]:
224.08000
[ PSA ]:
126.64000
[ LogP ]:
1.24060
[ Index of Refraction ]:
1.661
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AY6650000
- CHEMICAL NAME :
- Alanine, 3-(3-hydroxyanthraniloyl)-, L-
- CAS REGISTRY NUMBER :
- 606-14-4
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C10-H12-N2-O4
- MOLECULAR WEIGHT :
- 224.24
- WISWESSER LINE NOTATION :
- ZR BQ FV1YZVQ -L
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4408 mg/kg/21D-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - bronchiogenic carcinoma
- REFERENCE :
- JCROD7 Journal of Cancer Research and Clinical Oncology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.93- 1979- Volume(issue)/page/year: 96,163,1980
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 160 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - facilitates action of known carcinogen
- REFERENCE :
- ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 108,924,1963
Safety Information
[ HS Code ]:
2922509090
Customs
[ HS Code ]: 2922509090
[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%