6-AMINOPYRIMIDIN-2(1H)-ONE HYDROCHLORIDE
Names
[ CAS No. ]:
6047-01-4
[ Name ]:
6-AMINOPYRIMIDIN-2(1H)-ONE HYDROCHLORIDE
[Synonym ]:
6-Aminopyrimidin-2(1H)-one hydrochloride
1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one,monohydrochloride
(+/-)-cytisine hydrochloride
1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-on,Monohydrochlorid
Chemical & Physical Properties
[ Boiling Point ]:
218ºC at 2 MM HG
[ Melting Point ]:
152-153ºC
[ Molecular Formula ]:
C4H6ClN3O
[ Molecular Weight ]:
147.56300
[ Exact Mass ]:
147.02000
[ PSA ]:
71.77000
[ LogP ]:
0.73530
[ Storage condition ]:
2-8°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HA4200000
- CHEMICAL NAME :
- Cytisine hydrochloride
- CAS REGISTRY NUMBER :
- 6047-01-4
- LAST UPDATED :
- 199109
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C11-H14-N2-O.Cl-H
- MOLECULAR WEIGHT :
- 226.73
- WISWESSER LINE NOTATION :
- T C666 A GVN LM&TTJ &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 9400 ug/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy)
- REFERENCE :
- BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968- Volume(issue)/page/year: 35,161,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1730 ug/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy)
- REFERENCE :
- BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968- Volume(issue)/page/year: 35,161,1969
Safety Information
[ HS Code ]:
2933599090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%