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Ald-Ph-NHS ester

Names

[ CAS No. ]:
60444-78-2

[ Name ]:
Ald-Ph-NHS ester

[Synonym ]:
Benzaldehyde, 4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-
(2,5-dioxopyrrolidin-1-yl) 4-formylbenzoate
4-{[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl}benzaldehyde

Biological Activity

[Description]:

Ald-Ph-NHS ester is a nonclaevable linker for antibody-drug-conjugation (ADC).

[Related Catalog]:

Research Areas >> Cancer

[Target]

Noncleavable

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
425.4±47.0 °C at 760 mmHg

[ Melting Point ]:
163ºC

[ Molecular Formula ]:
C12H9NO5

[ Molecular Weight ]:
247.204

[ Flash Point ]:
211.1±29.3 °C

[ Exact Mass ]:
247.048065

[ PSA ]:
80.75000

[ LogP ]:
-0.20

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.606

[ Storage condition ]:
-20°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2925190090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Related Compounds

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