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Cucurbitacin A

Names

[ CAS No. ]:
6040-19-3

[ Name ]:
Cucurbitacin A

[Synonym ]:
19-Norlanosta-5,23-diene-3,11,22-trione,25-(acetyloxy)-2,16,20-trihydroxy-9-(hydroxymethyl)-,(2beta,9beta,10alpha,16alpha,23E)
Cucurbitacine A
Cucurbitacin A

Biological Activity

[Description]:

Cucurbitacin A, a triterpenoid that could be isolated from the Stems of Cucumis melo, shows anti-cancer activity[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

Cucurbitacin A inhibits the proliferation of A549 and BEL-7402 cells with IC50 values of 0.4 and 0.3 µM, respectively[1].

[References]

[1]. Chuan Chen, et al. Cucurbitane-type triterpenoids from the stems of Cucumis melo. J Nat Prod. 2009 May 22;72(5):824-9.

Chemical & Physical Properties

[ Density]:
1.27g/cm3

[ Boiling Point ]:
731ºC at 760 mmHg

[ Molecular Formula ]:
C32H46O9

[ Molecular Weight ]:
574.70200

[ Flash Point ]:
229.4ºC

[ Exact Mass ]:
574.31400

[ PSA ]:
158.43000

[ LogP ]:
2.47170

[ Index of Refraction ]:
1.58

Safety Information

[ Hazard Codes ]:
T

Related Compounds