Amethopterin

Names

[ Name ]:
Amethopterin

[Synonym ]:
amethopterin
4-amino-N10-methylpteroylglutamic acid
EINECS 262-213-7
MFCD00150845
4-amino-10-methylpteroyl-glutamic acid
D-methionine-R-sulfoximine
D-Methotrexat
2S,5S-Methionine sulfoximine

Chemical & Physical Properties

[ Density]:
1.536 g/cm3

[ Melting Point ]:
195ºC (dec.)(lit.)

[ Molecular Formula ]:
C₂₀H₂₂N₈O₅

[ Molecular Weight ]:
454.43900

[ Exact Mass ]:
454.17100

[ PSA ]:
210.54000

[ LogP ]:
1.82170

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MA1224100

CHEMICAL NAME :: Glutamic acid, N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)b enzoyl)-, DL-

CAS REGISTRY NUMBER :: 60388-53-6

LAST UPDATED :: 199610

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H22-N8-O5

MOLECULAR WEIGHT :: 454.50

WISWESSER LINE NOTATION :: T66 BN DN GN JNJ CZ EZ H1N1&R DVMYMQ2VQ -DL

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 32 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 29,43,1982

Safety Information

[ Hazard Codes ]:
T

[ Risk Phrases ]:
R46;R61

[ Safety Phrases ]:
S45-S53

[ RIDADR ]:
UN 1544 6.1/PG 2

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.