Fenarimol

Names

[ Name ]:
Fenarimol

[Synonym ]:
BLOC
rac-(R)-(2-chlorophenyl)(4-chlorophenyl)(pyrimidin-5-yl)methanol
(2-Chlorphenyl)(4-chlorphenyl)-5-pyrimidinylmethanol
α-(2-Chlorophenyl)-α-(4-chlorophenyl)-5-pyrimidinemethanol
EL 222
(±)-2,4'-Dichloro-α-(pyrimidin-5-yl)benzhydryl alcohol
(2-Chlorphenyl)(4-chlorphenyl)pyrimidin-5-ylmethanol
Rimidin
MFCD00055325
2,4'-Dichloro-α-(pyrimidin-5-yl)benzhydryl Alcohol
(RS)-2,4’-dichloro-α-(pyrimidin-5-yl)benzhydryl alcohol
T6N CNJ EXQR BG&R DG
(2-Chlorophenyl)(4-chlorophenyl)-5-pyrimidinylmethanol
5-Pyrimidinemethanol, α-(2-chlorophenyl)-α-(4-chlorophenyl)-
(2-chlorophenyl)-(4-chlorophenyl)-pyrimidin-5-ylmethanol
EINECS 262-095-7
Caswell No. 207AA
(2-Chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol
Rubigan
2,4'-Dichloro-α(pyrimidin-5-yl)benzhydryl alcohol
Fenarimol
(±)-Fenarimol
(2-Chlorophenyl)(4-chlorophenyl)5-pyrimidinylmethanol

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
502.6±45.0 °C at 760 mmHg

[ Melting Point ]:
117-119°C

[ Molecular Formula ]:
C₁₇H₁₂Cl₂N₂O

[ Molecular Weight ]:
331.196

[ Flash Point ]:
257.7±28.7 °C

[ Exact Mass ]:
330.032654

[ PSA ]:
46.01000

[ LogP ]:
3.22

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.643

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV9279400

CHEMICAL NAME :: 5-Pyrimidinemethanol, alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-

CAS REGISTRY NUMBER :: 60168-88-9

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C17-H12-Cl2-N2-O

MOLECULAR WEIGHT :: 331.21

WISWESSER LINE NOTATION :: T6N CNJ EXQR BG&R DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: >200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 980 mg/kg

SEX/DURATION :: male 4 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 450 mg/kg

REFERENCE :: DBANAD Doklady Bolgarskoi Akademii Nauk. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1948- Volume(issue)/page/year: 36,1351,1983

Safety Information

[ Symbol ]:

GHS08, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H361-H362-H411

[ Precautionary Statements ]:
P263-P273-P281

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R51/53;R62;R63;R64

[ Safety Phrases ]:
S36/37-S61

[ RIDADR ]:
UN 3017/3077

[ RTECS ]:
UV9279400

[ Hazard Class ]:
6.1

[ HS Code ]:
2933599016

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Genotoxic effects of the pesticides Rubigan, Omite and Rovral in root-meristem cells of Crepis capillaris L.

Mutat. Res. 652(2) , 191-7, (2008)

Three pesticides have been studied for their genotoxicity by the use of assays in the plant Crepis capillaris, aimed at measuring chromosomal aberrations, micronuclei and sister chromosome exchange (S...

Selective solid-phase extraction using molecularly imprinted polymer as a sorbent for the analysis of fenarimol in food samples.

Food Chem. 199 , 870-5, (2016)

In the present communication, a non-covalent fenarimol-imprinted polymer was synthesized by precipitation polymerization technique using methacrylic acid (MAA) as a functional monomer, ethylene glycol...

Development of a selective medium for the determination of the spore concentrations of Botrytis cinerea in the air.

Commun. Agric. Appl. Biol. Sci. 68(4 Pt B) , 685-93, (2003)

Gray mold, caused by Botrytis cinerea, is an important disease that causes world-wide extensive damage to a wide range of economically important crops. When it is necessary to determine the spore conc...