mercaptoethanol
Names
[ CAS No. ]:
60-24-2
[ Name ]:
mercaptoethanol
[Synonym ]:
emery5791
2-ME
mercaptoethanol
2-hydroxyethane-1-thiol
mercaptoethyl alcohol
2-Sulfanylethanol
2-sulfhydryl-ethanol
Bis-Mercaptoethanol
usafek-4196
β-Hydroxyethylmercaptan
β-mercaptoethanol
β-Hydroxyethanethiol
BME
Monothioglycol
Sipomer 2ME
2-mercapto-1-ethanol
Monothioethylene glycol
2-hydroxyethyl mercaptan
2-hydroxyethanethiol
2-Mercaptoethanol
2-THIOETHANOL
EINECS 200-464-6
MFCD00004890
Monothioethyleneglycol
Ethanol, 2-mercapto-
THIOGLYCOL
2-hydroxy ethanthiol
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
157.0±0.0 °C at 760 mmHg
[ Melting Point ]:
-100 °C
[ Molecular Formula ]:
C2H6OS
[ Molecular Weight ]:
78.133
[ Flash Point ]:
73.9±0.0 °C
[ Exact Mass ]:
78.013931
[ PSA ]:
59.03000
[ LogP ]:
-0.23
[ Vapour density ]:
2.69 (vs air)
[ Vapour Pressure ]:
1.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.479
[ Water Solubility ]:
soluble
[ Freezing Point ]:
<100℃
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KL5600000
- CHEMICAL NAME :
- Ethanol, 2-mercapto-
- CAS REGISTRY NUMBER :
- 60-24-2
- BEILSTEIN REFERENCE NO. :
- 0773648
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 20
- MOLECULAR FORMULA :
- C2-H6-O-S
- MOLECULAR WEIGHT :
- 78.14
- WISWESSER LINE NOTATION :
- SH2Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 244 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 ppm/8H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 190 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 13200 mg/m3
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 480 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 150 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 300 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3220 mg/kg/4W-I
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - mouse Cells - not otherwise specified
- DOSE/DURATION :
- 30 mmol/L
- REFERENCE :
- BBACAQ Biochimica et Biophysica Acta. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1947- Volume(issue)/page/year: 425,1,1976 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84674 No. of Facilities: 133 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 1437 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84674 No. of Facilities: 1497 (estimated) No. of Industries: 5 No. of Occupations: 13 No. of Employees: 14140 (estimated) No. of Female Employees: 4607 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS06, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301 + H331-H310-H315-H317-H318-H373-H410
[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P302 + P350-P305 + P351 + P338
[ Target Organs ]:
Heart, Liver
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R22;R24;R36/37/38;R51/53
[ Safety Phrases ]:
S26-S36/37/39-S45-S61-S29-S23
[ RIDADR ]:
UN 2966 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
KL5600000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
2930909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2930909090
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
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Ubiquitylation regulates a multitude of biological processes and this versatility stems from the ability of ubiquitin (Ub) to form topologically different polymers of eight different linkage types. Wh...
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Onychomycosis is a fungal infection mostly induced by dermatophytes such as Trichophyton rubrum. Due to slow nail growth, the treatment takes 3-9 months depending on the nail size and infected area. H...