Isopropyl ferulate

Names

[ Name ]:
Isopropyl ferulate

[Synonym ]:
Trans-isopropyl ferulate
4-Hydroxy-3-methoxycinnamic acid isopropyl ester
CINNAMIC ACID,4-HYDROXY-3-METHOXY-,ISOPROPYL ESTER
Isopropyl ferulate

Biological Activity

[Description]:

Isopropyl ferulate, isolated from Rhizoma et Radix Notopterygii (Qianghuo), is used in the reduction of pharmaceuticals, preparation of antifungal agents, cosmetics and as antioxidant agent and so forth[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Kumar A, et al. Synthesis of isopropyl ferulate using silica-immobilized lipase in an organic medium. Enzyme Res. 2011;2011:718949.

[2]. Li F, et al. Anti-austerity agents from Rhizoma et Radix Notopterygii (Qianghuo). Planta Med. 2012 May;78(8):796-9.

Chemical & Physical Properties

[ Density]:
1.145g/cm3

[ Boiling Point ]:
358.2ºC at 760mmHg

[ Molecular Formula ]:
C₁₃H₁₆O₄

[ Molecular Weight ]:
236.26400

[ Flash Point ]:
131.9ºC

[ Exact Mass ]:
236.10500

[ PSA ]:
55.76000

[ LogP ]:
2.36560

[ Index of Refraction ]:
1.556

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD9450000

CHEMICAL NAME :: Cinnamic acid, 4-hydroxy-3-methoxy-, isopropyl ester

CAS REGISTRY NUMBER :: 59831-94-6

LAST UPDATED :: 199309

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C13-H16-O4

MOLECULAR WEIGHT :: 236.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1059 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 25,187,1987

Safety Information

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%