Cantabiline sodium
Names
[ CAS No. ]:
5980-33-6
[ Name ]:
Cantabiline sodium
[Synonym ]:
mendiaxon sodium salt
4-methyl-7-hydroxy-2H-1-benzopyran-2-one sodium salt
LM 94 sodium
hymercromone
Mendiaxon Sodium
7-hydroxy-4-methylcoumarin sodium salt
Hymecromone sodium
Sodium 4-methylumbelliferone
hymecromonum sodium salt
4-Methylumbelliferone sodium
EINECS 227-790-1
Methyl 4 umbelliferone sodium
4-Methylumbelliferone sodium salt
7-Hydroxy-4-methylcoumarin sodium
Cantabiline sodium
Chemical & Physical Properties
[ Density]:
1.319g/cm3
[ Boiling Point ]:
377.4ºC at 760 mmHg
[ Melting Point ]:
90-92ºC(lit.)
[ Molecular Formula ]:
C10H7NaO3
[ Molecular Weight ]:
198.15100
[ Flash Point ]:
174.5ºC
[ Exact Mass ]:
198.02900
[ PSA ]:
53.27000
[ LogP ]:
2.24520
[ Index of Refraction ]:
1.611
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GN7570000
- CHEMICAL NAME :
- Coumarin, 7-hydroxy-4-methyl-, sodium salt
- CAS REGISTRY NUMBER :
- 5980-33-6
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C10-H7-O3.Na
- MOLECULAR WEIGHT :
- 198.16
- WISWESSER LINE NOTATION :
- T66 BOVJ E1 IQ &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 23,359,1968
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 292 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 23,359,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 325 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 23,359,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 23,359,1968
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 283 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 23,359,1968
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 235 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 23,359,1968
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
T+
[ Risk Phrases ]:
26/27/28
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
GN7570000
Precursor & DownStream
Precursor
DownStream
Articles
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The aim of this study was to characterize the interaction of KYSE-410, an esophageal squamous cell carcinoma cell line, and fibroblasts with respect to the extracellular matrix component hyaluronan (H...
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The industrial use of elicitors as alternative tools for disease control needs the identification of abundant sources of them. We report on an elicitor obtained from the green algae Ulva spp. A fracti...
Acid stability of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity.PLoS Pathog. 7 , e1002398, (2011)
Highly pathogenic avian influenza viruses of the H5N1 subtype continue to threaten agriculture and human health. Here, we use biochemistry and x-ray crystallography to reveal how amino-acid variations...