1,2-Dimethylpropylamine
Names
[ CAS No. ]:
598-74-3
[ Name ]:
1,2-Dimethylpropylamine
[Synonym ]:
3-Methylbutan-2-amine
MFCD00008081
3-Methyl-2-butanamine
EINECS 209-949-7
3-Methylbutan-2-amin
UNII:1P7J19TM9E
2-Butanamine, 3-methyl-
Chemical & Physical Properties
[ Density]:
0.8±0.1 g/cm3
[ Boiling Point ]:
85.5±0.0 °C at 760 mmHg
[ Melting Point ]:
−50 °C(lit.)
[ Molecular Formula ]:
C5H13N
[ Molecular Weight ]:
87.163
[ Flash Point ]:
-27.8±0.0 °C
[ Exact Mass ]:
87.104797
[ PSA ]:
26.02000
[ LogP ]:
1.09
[ Vapour Pressure ]:
69.2±0.1 mmHg at 25°C
[ Index of Refraction ]:
1.411
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UI1100000
- CHEMICAL NAME :
- Propylamine, 1,2-dimethyl-
- CAS REGISTRY NUMBER :
- 598-74-3
- BEILSTEIN REFERENCE NO. :
- 0635656
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C5-H13-N
- MOLECULAR WEIGHT :
- 87.19
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536386
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536386 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 510 uL/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - tremor Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536386
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 279 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 17,475,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 810 uL/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - changes in structure or function of salivary glands Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536386
Safety Information
[ Symbol ]:
GHS02, GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H302 + H312-H314
[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
F:Flammable;C:Corrosive;
[ Risk Phrases ]:
R11;R21/22;R34
[ Safety Phrases ]:
S16-S26-S27-S36/37/39-S45
[ RIDADR ]:
UN 3286 3/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
UI1100000
[ Packaging Group ]:
II
[ Hazard Class ]:
3
Synthetic Route
Articles
Anal. Chim. Acta 653(2) , 228-33, (2009)
A fast separation of alkali and alkaline earth metal cations and ammonium was carried out by capillary electrochromatography on monolithic octadecylsilica columns of 15 cm length and 100 μm inner diam...