Prosultiamine
Names
[ CAS No. ]:
59-58-5
[ Name ]:
Prosultiamine
[Synonym ]:
Aneurimec
tiotiamina
Prosultiamine
2-(2-Methyl-4-aminopyrimidin-5-yl)methylformamido-5-hydroxy-2-penten-3-yl Propyl Disulfide
Alinamine
TPD
Sintotiamina
neurvita
Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[(1E)-4-hydroxy-1-methyl-2-(propyldithio)-1-buten-1-yl]-
Proneurin
nervilon
N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[(2E)-5-hydroxy-3-(propyldisulfanyl)-2-penten-2-yl]formamide
DTPT
EINECS 200-436-3
nevriton
Nuvelbi V.C.A.
alinamin
N-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-N-[(2E)-5-hydroxy-3-(propyldisulfanyl)pent-2-en-2-yl]formamide
aliton
thiamine propyldisulfide
tipidi
nuvelbiv.c.a.
arinamine
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
593.7±50.0 °C at 760 mmHg
[ Molecular Formula ]:
C15H24N4O2S2
[ Molecular Weight ]:
356.507
[ Flash Point ]:
312.9±30.1 °C
[ Exact Mass ]:
356.134064
[ PSA ]:
142.94000
[ LogP ]:
3.41
[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C
[ Index of Refraction ]:
1.620
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LQ0699000
- CHEMICAL NAME :
- Formamide, N-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(4-hydro xy-1-methyl-2- (propyldithio)-1-butenyl)-
- CAS REGISTRY NUMBER :
- 59-58-5
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C15-H24-N4-O2-S2
- MOLECULAR WEIGHT :
- 356.55
- WISWESSER LINE NOTATION :
- T6N CNJ B1 DZ E1NVHY1&UY2QSS3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,724,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 650 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,724,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,724,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 37500 mg/kg/15D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- REFERENCE :
- INDRBA Indian Drugs. (Indian Drugs Manufacturers' Assoc., 102B, Poonam Chambers, Dr. A. B. Rd., Worli, Bombay 400 018, India) V.1- 1963- Volume(issue)/page/year: 12,13,1974/1975
Safety Information
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
26-36/37/39