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Urea,N-(2-chloroethyl)-N'-(2,6-dihydroxycyclohexyl)-N-nitroso-, (1a,2b,6b)- (9CI)

Names

[ CAS No. ]:
58484-17-6

[ Name ]:
Urea,N-(2-chloroethyl)-N'-(2,6-dihydroxycyclohexyl)-N-nitroso-, (1a,2b,6b)- (9CI)

Chemical & Physical Properties

[ Density]:
1.58g/cm3

[ Molecular Formula ]:
C9H16ClN3O4

[ Molecular Weight ]:
265.69400

[ Exact Mass ]:
265.08300

[ PSA ]:
102.23000

[ LogP ]:
0.58340

[ Index of Refraction ]:
1.628

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YS4906350
CHEMICAL NAME :
Urea, N-(2-chloroethyl)-N'-(2,6-dihydroxycyclohexyl)-N-nitr oso-, (1-alpha,2-beta,6-beta)-
CAS REGISTRY NUMBER :
58484-17-6
LAST UPDATED :
198610
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H16-Cl-N3-O4
MOLECULAR WEIGHT :
265.73
WISWESSER LINE NOTATION :
L6TJ AQ BMVNNO&2G CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
33010 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
11500 ug/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 6,25,1981

Related Compounds

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