Glycine ethyl ester-13C hydrochloride

Names

[ CAS No. ]:
58420-91-0

[ Name ]:
Glycine ethyl ester-13C hydrochloride

[Synonym ]:
Ethyl Glycinate-2-13C Hydrochloride
Ethyl 2-Aminoacetate-2-13C Hydrochloride
Glycine-2-13C Ethyl Ester Hydrochloride
Aminoacetic Acid-2-13C Ethyl Ester Hydrochloride
Glycine-2-13C Ethyl Ester Monohydrochloride
Ethyl Aminoacetate-2-13C Hydrochloride

Biological Activity

[Description]:

Glycine ethyl ester-13C (hydrochloride) is a 13C-labeled Mebendazole.

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Research Areas >> Infection

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-233.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-233.

Chemical & Physical Properties

[ Molecular Formula ]:
C313CH10ClNO2

[ Molecular Weight ]:
140.57

[ Exact Mass ]:
140.04300

[ PSA ]:
52.32000

[ LogP ]:
1.01050

Synthetic Route

Click to get detail synthetic route

Related Compounds