Benzamide,4-amino-N-(2-aminophenyl)-
Names
[ CAS No. ]:
58338-59-3
[ Name ]:
Benzamide,4-amino-N-(2-aminophenyl)-
[Synonym ]:
Goe-1734
4-Amino-N-(2'-aminophenyl)-benzamide
Dinaline [INN]
Dinalina [Spanish]
2',4-Diaminobenzanilide
Dinaline [French]
2',4-Diaminobenzanilid
Dinaline
Dianiline
Dinalinum [Latin]
Chemical & Physical Properties
[ Density]:
1.314g/cm3
[ Boiling Point ]:
367.2ºC at 760mmHg
[ Molecular Formula ]:
C13H13N3O
[ Molecular Weight ]:
227.26200
[ Flash Point ]:
175.9ºC
[ Exact Mass ]:
227.10600
[ PSA ]:
81.14000
[ LogP ]:
3.33870
[ Index of Refraction ]:
1.734
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CU8994000
- CHEMICAL NAME :
- Benzamide, 4-amino-N-(2-aminophenyl)-
- CAS REGISTRY NUMBER :
- 58338-59-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C13-H13-N3-O
- MOLECULAR WEIGHT :
- 227.29
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 95 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 625 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 630 mg/kg/6W-I
- TOXIC EFFECTS :
- Blood - changes in bone marrow (not otherwise specified) Blood - changes in erythrocyte (RBC) count Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 462 mg/kg/14W-I
- TOXIC EFFECTS :
- Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6678 mg/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Endocrine - adrenal cortex tumors Reproductive - Maternal Effects - uterus, cervix, vagina
MUTATION DATA
- TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- REFERENCE :
- CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 69,1415,1985