2-bromohydroquinone
Names
[ CAS No. ]:
583-69-7
[ Name ]:
2-bromohydroquinone
[Synonym ]:
2-Bromo-1,4-benzenediol
2-bromobenzene-1,4-diol
EINECS 209-516-2
2-bromohydroquinone
MFCD00041747
1,4-Benzenediol, 2-bromo-
Chemical & Physical Properties
[ Density]:
1.8±0.1 g/cm3
[ Boiling Point ]:
278.3±20.0 °C at 760 mmHg
[ Melting Point ]:
112-116 °C(lit.)
[ Molecular Formula ]:
C6H5BrO2
[ Molecular Weight ]:
189.007
[ Flash Point ]:
122.1±21.8 °C
[ Exact Mass ]:
187.947281
[ PSA ]:
40.46000
[ LogP ]:
2.01
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.657
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CZ8920000
- CHEMICAL NAME :
- 1,4-Benzenediol, 2-bromo-
- CAS REGISTRY NUMBER :
- 583-69-7
- BEILSTEIN REFERENCE NO. :
- 2042870
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C6-H5-Br-O2
- MOLECULAR WEIGHT :
- 189.02
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 87200 ug/kg
- SEX/DURATION :
- female 9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 120,1,1993
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
CZ8920000
[ HS Code ]:
2908199090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2908199090
[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%
Articles
Chem. Res. Toxicol. 5(4) , 561-7, (1992)
Bromobenzene is metabolized to electrophilic epoxides and quinones which covalently bind to protein sulfur nucleophiles, yet no quinone-derived mercapturic acid metabolites of bromobenzene have been r...
Inhibition of respiration in rabbit proximal tubules by bromophenols and 2-bromohydroquinone.Adv. Exp. Med. Biol. 197 , 911-7, (1986)
Cellular toxicity of bromobenzene and bromobenzene metabolites to rabbit proximal tubules: the role and mechanism of 2-bromohydroquinone.
J. Pharmacol. Exp. Ther. 237(2) , 456-61, (1986)
An in vitro model using a suspension of rabbit renal proximal tubules was developed to investigate the mechanism of nephrotoxicity of bromobenzene. Using oxygen consumption, glutathione concentrations...