2-Naphthylacetic acid
Names
[ CAS No. ]:
581-96-4
[ Name ]:
2-Naphthylacetic acid
[Synonym ]:
2-Naphthaleneacetic acid
2-Naphthylacetic acid
naphthalen-2-ylacetic acid
2-Naphthalene acetic acid
2-naphthalen-2-ylacetic acid
EINECS 209-475-0
MFCD00004126
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
373.2±11.0 °C at 760 mmHg
[ Melting Point ]:
141-143 °C(lit.)
[ Molecular Formula ]:
C12H10O2
[ Molecular Weight ]:
186.207
[ Flash Point ]:
270.1±14.4 °C
[ Exact Mass ]:
186.068085
[ PSA ]:
37.30000
[ LogP ]:
2.74
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.652
[ Water Solubility ]:
insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QJ0876000
- CHEMICAL NAME :
- 2-Naphthaleneacetic acid
- CAS REGISTRY NUMBER :
- 581-96-4
- LAST UPDATED :
- 198502
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C12-H10-O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 116,154,1958
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
QJ0876000
[ HS Code ]:
29163900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Biomacromolecules 15(10) , 3559-68, (2014)
Peptides made of D-amino acids, as the enantiomer of corresponding L-peptides, are able to resist proteolysis. It is, however, unclear or much less explored whether or how D-amino acids affect the cel...
Differentiation of esterases reacting with organophosphorus compounds.Chem. Biol. Interact. 87(1-3) , 77-83, (1993)
The hydrolysis of paraoxon (POX), phenylacetate (PA) and beta-naphthylacetate (BNA) was studied in human serum. Based upon correlations between enzyme activities, upon reversible inhibition by EDTA an...
Ceramide participates in lysosome-mediated cell death induced by type II anti-CD20 monoclonal antibodies.Leuk. Lymphoma 56 , 1863-8, (2015)
Considering the variable and often modest therapeutic efficacy of rituximab for a substantial proportion of patients suffering from non-Hodgkin lymphomas (NHLs), various type II anti-CD20 monoclonal a...