3,4-Dichlorophenylacetic acid
Names
[ CAS No. ]:
5807-30-7
[ Name ]:
3,4-Dichlorophenylacetic acid
[Synonym ]:
2-(3,4-dichlorophenyl)acetic acid
Benzeneacetic acid, 3,4-dichloro-
(3,4-Dichlorophenyl)acetic acid
EINECS 227-368-7
MFCD00004333
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
328.0±27.0 °C at 760 mmHg
[ Melting Point ]:
89-91 °C(lit.)
[ Molecular Formula ]:
C8H6Cl2O2
[ Molecular Weight ]:
205.038
[ Flash Point ]:
152.1±23.7 °C
[ Exact Mass ]:
203.974487
[ PSA ]:
37.30000
[ LogP ]:
2.57
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.585
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2916399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
J. Med. Chem. 32 , 1996, (1989)
The synthesis and in vitro sigma receptor activity of the two diastereomers of U50,488 [(+/-)-2], namely, (1R,2S)-(+)- cis-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacet ami de [(+)...
4-[(Alkylamino)methyl]furo[3,2-c]pyridines: a new series of selective kappa-receptor agonists.J. Med. Chem. 37 , 2138, (1994)
The synthesis of 5-(arylacetyl)-4-[(alkylamino)methyl]furo[3,2-c] pyridines (16-23, 26, 27) and their activities as kappa-opioid receptor agonists are described. kappa-Agonist potency was particularly...